In June 2007, the Ministry of Railways launched a project feasibility study & preliminary designs, which were completed in November 2007.

For up to six months before the high-speed railway was completed, the Shenzhen North Station subway and bus shuttle transfer hall functioned.

The high-speed rail section of the Shenzhen North railway station had repeatedly delayed the opening time.

On December 26, 2011 morning, the Guangzhou-Shenzhen-Hong Kong Express Rail Link's Guangzhou-Shenzhen section, opening ceremony was held in Shenzhen North Station, with the Minister of Railways Sheng Guangzu, the Guangdong Provincial Party Secretary Wang Yang, the former governor of Guangdong Province Huang Hua Hua and acting governor of Guangdong Zhu Xiaodan, who attended the ceremony.

[16] Among them, the high-speed railway was in a north-south direction, with the station building located on the top of the tracks ; the East Square is dominated by public transport interchange; West Plaza has most of the private car parking and long distance bus terminal.

The Pingnan Railway runs from east to west under the entire station but has no platforms and no services stop on this line.

[16] Platforms As of October 2012, Shenzhen North station is the terminal for numerous G-series trains on the Shenzhen-Guangzhou-Wuhan-Zhengzhou high-speed line.

[17] Commencing on December 26, 2012, trains now operate between Shenzhen North and Beijing West, making it the longest high speed rail journey possible in the world.

Some C-series trains to Guangzhou, as well as various "conventional" trains to destinations throughout China leave from Shenzhen railway station; in the past there was also a much less busy Shenzhen West railway station providing passenger service while such function has been transferred to Shenzhen East railway station that passenger service has already been opened in December 2012 to handle conventional train services.