It carried three People's Liberation Army Astronaut Corps (PLAAC) taikonauts on board a Shenzhou spacecraft.

[8] The crew also oversaw the expansion of Tiangong with the addition of the Wentian and Mengtian laboratory cabin modules, which arrived at the station in July and October 2022 respectively.

The crew of Shenzhou 14 opened the hatch and entered Wentian for the first time on 25 July 2022 at 02:03 UTC, to perform an inspection of the module.

The two exited the airlock of the Wentian lab module and completed a series of tasks, including installing an extended pump set on the exterior of the station, raising panoramic camera B, installing a workbench, and demonstrating procedures for an emergency return to the airlock.

Chen and Cai completed the installation of foot restraints and extravehicular workbenches with support from the station's small robotic arm, performed further work on the extended pump set, and further verified EVA emergency rescue procedures.

[14][15] On 12 October 2022 at 4:01 PM China Standard Time (08:01 UTC), the crew of Shenzhou 14 conducted a live "space lecture" broadcast.

During the lecture, Chen Dong and Liu Yang introduced the functions of the Wentian module and conducted scientific experiments as part of a science lesson while Cai Xuzhe filmed.