[2][3][4][5] Mirzo was born in 1967 in the Moskovskiy District (present-day Hamadoni) in the Khatlon Region in the Tajik Soviet Socialist Republic.

In 1994-1995 he was a senior officer of the military training department of the Ministry of Defense and from 1997-2002, he was the commander of the 7th Separate Motor Rifle Battalion.

From 2005–2006, he served as Tajikistan’s Deputy Minister of Defence before being moving to the State Committee for National Security (SCNS) which succeeded the KGB of the Tajik SSR.

On 3 October 2013 by order of a presidential decree he was appointed Minister of Defense by President Emomali Rahmon.

[14] In 2021, he visited Tehran, agreeing with General Mohammad Baqeri to establish a joint defensive and military committee between the National Army and the Islamic Republic of Iran Armed Forces.