The Vert et Or first began to play in 1971 in the Quebec Universities Athletic Association as the Sherbrooke Estrien.

The current football program has seen mixed success, with teams only qualifying for the postseason twice in its first seven years.

However, the Vert et Or made progress after posting their first winning season in 2008 followed by their first appearance in the Dunsmore Cup championship in 2010, losing a close game to the Laval Rouge et Or.

[3] Then, in 2011, Sherbrooke finished in 2nd place in the Quebec conference and hosted their first playoff game.

[4] In 2021, the Sherbrooke Vert et Or beat the Laval Rouge et Or for the first time in its history, at home, with a final score of 23-17.