The great detective Sherlock Holmes and his trusted companion Dr. John Watson travel to New York City to investigate a recent threat made by Professor Moriarty.

During their investigation, Holmes and Watson are reunited with their old acquaintance Irene Adler, now a popular music-hall singer, who reveals that Moriarty has kidnapped her son.

Holmes is subsequently contacted by the NYPD regarding the recent apparent theft of the international gold exchange at the New York bank, with the entire vault of gold bars having vanished seemingly overnight, the theft only secret until a planned transaction between Italy and Germany in three days' time.

[3] The film was scored by Richard Rodney Bennett, marking his first work for American television; Leonard Rosenman conducted.

On 9 October 2006, Intrada Records released the music on a limited edition CD alongside Georges Delerue's score for The Pick-up Artist.