Sheryl Lee Sculley (born May 1, 1952) is an American politician and the former city manager of San Antonio, Texas, a position which she filled from November 2005 until March 2019.

Among her achievements in San Antonio, Sculley pushed for the $325 million expenditure in 2016 to renovate the downtown Henry B. González Convention Center.

In 2015, at the annual gathering of the San Antonio Convention & Visitors Bureau, Sculley was honored with the Robert H. H. Hugman Award for her contributions to the city.

She worked in 2016 to make the Convention & Visitors Bureau into a public-private nonprofit organization renamed Visit San Antonio.

Michael Sculley was appointed by the Bexar County Commissioners Court as director of the Community Venues Program Office.