The group performs at the NMB48 Theater, which is located in the basement of the Yes-Namba Building in Namba, Osaka.

On July 10, 2010, AKB48 first announced that they would be forming a second sister national group, based in Namba.

[4] This makes NMB48 the second girl group after Passpo to reach number 1 with a debut single.

[4] On August 24, 2012, the first day of AKB48's Tokyo Dome Concert, it was revealed that Team A member Yui Yokoyama would also hold a position in NMB48.

[5] On September 3, Eriko Jo, a member of Team M, announced that she would be leaving the group during the performance at the theater.

Following Jo's graduation, two members from Team M announced their resignation in early October.

On the same day Sayaka Yamamoto announced her resignation from AKB48's Team K.[14] On April 27, 2016, the group released their 14th single Amagami Hime.

On June 15, 2018, 6 members of NMB48 (Cocona Umeyama, Kokoro Naiki, Yuuka Kato, Miru Shiroma, Azusa Uemura and Sae Murase) joined Produce 48.

Kokoro Naiki, Yuuka Kato, Sae Murase and Miru Shiroma ranked 87, 74, 22 and 20 respectively.

On July 30, 2018, Sayaka Yamamoto, captain of Team N announced in NMB48 LIVE TOUR 2018 in Summer that she would be graduating from NMB48.

The winner of the project would earn the opportunity to get a new song and music video as part of NMB48's next release, as well as a new theatre stage and adjusted media appearances.

[18] On the same date, the project NAMBATTLE 2 was also announced, which, alongside other programmes, also include a general election for NMB48 members that will be held on March 27, 2022.

The winner of the event was Chihiro Kawakami with 21,462 votes, and she will subsequently be the center for NMB48's 27th single.