Shiloh is an unincorporated community on Middle Island Creek in Tyler County, West Virginia, United States.

The first white settlers in what is now Tyler County, WV came in the late 1790s or very early 19th century.

Jacob and his wife Druscilla Ankrom purchased land along Middle Island Creek.

Jacob Cornell and his wife Druscilla Ankrom remained buried on this land until this day.

The town is also the namesake for the fictional beagle dog in the children's book quartet Shiloh (novel), written by Phyllis Reynolds Naylor.