The Shiloh Missionary Baptist Church and Rosenwald School is a historic Missionary Baptist Church and Rosenwald School located near 7794 Highway 81, Notasulga, Alabama in Macon County, Alabama.

The Rosenwald School, built c. 1922 and remodeled c. 1936, retains its historical and architectural integrity from the 1930s when a New Deal agency expanded the industrial room and made other interior and exterior changes.

One of the most infamous incidents in the medical history of the United States is the study of syphilis, sponsored by the U. S. Public Health Service (USPHS) in Macon County, Alabama, from 1932 to 1973.

The Shiloh Missionary Baptist Church is located about 8 miles north of Tuskegee, Alabama.

The buildings and adjacent cemetery were added to the Alabama Register of Landmarks and Heritage on September 20, 2006.