A creative midfielder who often acts as a deep-lying playmaker, Cruz is the second-ever female footballer behind Gabriela Trujillo from Costa Rica to play in Europe when she joined Lyon in 2005.

In the Challenge de France, Cruz was instrumental in helping Lyon reaching the final, where they lost to Montpellier on penalties scoring four goals in five appearances.

She also appeared in all seven UEFA Women's Cup matches, where Lyon suffered elimination in the semi-finals after losing 2–4 on aggregate to German club FCR 2001 Duisburg.

[6] In March 2020, Cruz signed with OL Reign for the 2020 NWSL season,[7] which due to the pandemic, was reformatted and condensed to shorter post tournament style competitions, the Challenge Cup and Fall Series.

[13] On June 8, 2023, after unexpectedly not being selected to the national team roster for the 2023 FIFA Women's World Cup,[14] Cruz announced her retirement from football on social media.

Following a match in 2004 against Canada, in which she suffered a sprained right knee, Cruz did not feature with the national team for the next two years, due to commitments with her football club.