The Prefectural Highway 305 (Ebisu-dori) divides Shirokane into odd-numbered (1, 3, 5-chōmes) and even-numbered (2, 4, 6-chōmes) subdistricts designated as industrial and high-rise residential areas, respectively.

The recent opening of a subway allowed the area centered at Shirokane-Takanawa Station to undergo a large redevelopment.

This large green area dates back to daimyō's mansions which existed in Edo period; later, industrialists made their residences in this place, which gave rise to the well-known upper-class neighborhood.

His nickname was Shirokane Chōja (白金長者), which means "man who possesses much 'white gold' " (白金), a reference to silver.

Shirokane 1 and 3-6 chōme and 2-chōme 1-5-ban are zoned to Shirogane-no-oka Gakuen (白金の丘学園) for elementary and junior high school.