[2] Ghai began her acting career on the London stage, working for companies such as Man Mela, Rifco and Kali.
[2][5] After this, Ghai appeared in BBC shows such as My Hero and Sinchronicity, short films, theatre and commercials.
In 2006, she was cast as Sarita Dhavi in Rai Uno's Un medico in famiglia,[5] the popular Italian television programme, when an Indian family was added to the show.
[2][1] In 2009, Ghai filmed a guest lead as Jamilla Sagar, in a series called Identity, starring Aidan Gillen and Keeley Hawes.
[6] She was also noted in the press for standing out amongst an ensemble cast that included Suranne Jones, Anne Reid, David Morrissey, Bernard Hill, and Steve Evets.
[7][8][9] She played the part of Rena in the film Cleanskin, which starred Sean Bean and Charlotte Rampling.
In 2019, she appeared in Strike Back: Revolution as a very wealthy Hindu entrepreneur and one of the main villains of the series.