The men's 50 metre pistol shooting event at the 2011 Pan American Games was held on October 18 at the Jalisco Hunting Club in Guadalajara.

[1] The defending Pan American Games champion was Jason Turner of the United States.

In the qualifier, each shooter fired 60 shots with a pistol at 50 metres distance.

Sergio Sanchez of Guatemala won the competition, which qualified his country a quota spot for the men's 50 metre pistol event at the 2012 Summer Olympics in London, Great Britain.

The existing world and Pan American Games records were as follows.