[1] As of June 2021, Ungerleider is the host and producer of the TED Health[2] and Before We Go podcasts,[3] practices internal medicine, runs a non-profit that she founded, End Well,[4] and during the COVID-19 pandemic, contributed regularly as a medical expert on CNN,[5] MSNBC, CBS and Fox News.

As a journalist, she has published articles about end of life and other medical topics in popular media including Newsweek,[14] USA Today,[15] Scientific American, TIME, Vox, San Francisco Chronicle and Stat and has appeared regularly as a medical expert contributor on CNN,[16] MSNBC and Fox News as well as PBS NewsHour and CBSN.

In film, Ungerleider executive produced Netflix's Academy Award-nominated short documentary, End Game,[17] by directors Rob Epstein and Jeffrey Friedman.

[23] Ungerleider founded endwellproject.org in 2017, a non-profit organization focused on education and awareness to improve the end of life experience where she remains President of the Board of Directors.

Its perspective ranges from culture, healthcare, design, business, technology to policy where notable individuals such as actress Taraji P. Henson,[26] country music singer Tim McGraw, Bravo (American TV channel) reality host Andy Cohen, Dr. Atul Gawande, Dr. BJ Miller,[27] singer Melissa Etheridge and others have spoken.