Shrule (Irish: Sruthair, also anglicised to Shruel, usage deprecated) is a village in County Mayo in Ireland.

[2] The ruin of Shrule Castle, a fortification built by the Norman de Burgo family, dominates the view of the village as approached from the Galway side.

The two branches of the Burke family, the MacWillams of Mayo and the Clanricardes of Galway, held a lot of territory and influence.

After breaking out from a siege in Galway, he besieged Shrule Castle with the support of Richard Burke, Earl of Clanricarde.

Edmond Bourke, an Irish soldier who led the escort duty, and a cousin of Lord Mayo, then ordered their troops to begin killing their settler charges.

Though Mayo's son Theobald tried to save some prisoners, and had to be driven away, he was executed in 1653 by a Parliamentarian inquiry for complicity in the killings that was held after the Cromwellian conquest of Ireland.

The Mortimer brothers Conor, Trevor and Kenneth have all appeared for the Mayo County Senior Football team.

Christopher O'Dowd, a native of Shrule, was an original member of the Special Air Service British regiment.