Sibling Rivalry (Family Guy)

[1] The episode follows Stewie as he battles with his half-brother, Bertram (voiced by Wallace Shawn), who is born to two lesbians after Peter donates sperm.

A lesbian couple use one of the samples to conceive a child, giving birth to Bertram, who first appeared in the episode "Emission Impossible".

Eventually, Lois's heart gives out during sex and she is rushed to the hospital, where the doctors remove all of the excess fat and return her to normal size.

Lois admits that eating is not a good way to solve problems, and Peter states he loves her no matter her size, but is later caught kissing the fat in a storage closet.

The song performed after Lois' pregnancy test comes back negative was written by Alec Sulkin and Alex Borstein, and sung by professional Hollywood studio singers.

[3] The sketch of Peter challenging Lois to a race to Boston was removed from television broadcasting in order to save time.

[4] As Lois is slowly racing Peter to Boston, a Shania Twain song can be heard on the radio; Dan Povenmire states on the DVD commentary that he often gets into trouble for adding pieces of music into an episode when they're so short, yet cost so much.

[4] An un-used scene was intended for broadcasting which showed Stewie, while trying to find Waldo in an Abercrombie & Fitch catalog, saying to Brian "Oh, turn to the next page.

[3][5] In addition to the regular cast, actors Randy Crenshaw, Gavin Dunne, Bob Joyce, John Joyce, Rick Logan, and Wallace Shawn, and voice actors Phil LaMarr, Tara Strong, Nicole Sullivan, and Wally Wingert guest starred in the episode.

Recurring voice actor Ralph Garman, and writers Mike Henry, Chris Sheridan, Danny Smith, Alec Sulkin, and John Viener made minor appearances.

When in the children's park, Stewie quotes "Did ya get me my Cheez Whiz, boy" and a man throws one to him, this is a reference to The Blues Brothers.

This leads to a hysterical, yet truly gross, scene where Peter knocks over an entire shelf of sperm samples, and has to refill them, um, himself.

Dan Povenmire directed the episode.