He was one of several Gauls who rose to political prominence in the late 4th century as a result of the emperor Gratian's appointment of his Bordelaise tutor Ausonius to high office.
The medical writer Marcellus, their countryman, places Siburius in the company of the historian Eutropius and Julius Ausonius, father of the political scholar-poet, as peers with a literary expertise in medicine.
[9] Siburius is the addressee of three letters among the correspondence of Quintus Aurelius Symmachus, the advocate of religious tolerance who attempted to preserve the traditional religions of Rome at a time when Christianity had become dominant.
[10] Symmachus teases Siburius about his archaic writing style (ἀρχαϊσμὸν scribendi):[11] If you're so in love with the old days, let's return with an equal amount of attention to the time-honored words in which the Salian priests chanted and the augurs pronounced on a bird-omen and the Commission of Ten established the legal code.
[12]In the assessment of commentator Andrea Pellizzari, Siburius was indeed "un uomo di grande cultura," a highly cultured person.