[1][2] The band's lineup consists of brothers Lou and Pete Koller on lead vocals and guitars respectively, Armand Majidi on drums, and Craig Setari on bass.

Sick of It All is considered a major part of the New York hardcore scene,[3] and by 2020, the band had sold at least half a million records worldwide.

After this performance, Lamb and McNeely left the band, leading to the brothers hiring Rich Cipriano as bassist and Armand Majidi as a "fill-in" drummer.

Despite containing some of the band's favored live tracks, including "Blown Away", "The Bland Within", "District" and "America", some fans felt alienated by the album's progressive nature and in a recent interview, frontman Lou Koller claimed that the album's cover art probably contributed to its poor reception.

In 2004, the band also released an album of B-sides, covers and rare tracks entitled Outtakes for the Outcast, which contains some Sick of It All recordings.

A tribute to the band, titled Our Impact Will Be Felt, was released on April 24, 2007, and includes covers from artists such as Bane, Bleeding Through, the Bouncing Souls, Ignite, Comeback Kid, Hatebreed, Himsa, Madball, Most Precious Blood, Napalm Death, Pennywise, Rise Against, Sepultura, Stretch Arm Strong, the Suicide Machines, Unearth, and Walls of Jericho.

In an August 2009 interview with singer Lou Koller, he revealed that the band would begin recording their new album in November for a 2010 release.

In November 2011, singer Lou Koller revealed to AbsolutePunk writer Dre Okorley that Sick of It All had begun writing a follow-up to Based on a True Story.

[15] By December 2016, Sick of It All had begun working on their twelfth studio album,[16] Wake the Sleeping Dragon!, which was released on November 2, 2018.

Following the announcement, vocalist Lou Koller revealed his diagnosis with an esophageal tumor, which would require treatment over the course of the summer.

[19] They have cited influences including Agnostic Front, Reagan Youth,[21] the Exploited,[22] Discharge, GBH and Motörhead.

Guitarist Pete Koller was influenced to play guitar in a band by the Plasmatics and Black Sabbath.