He initially worked as hired henchman alongside Anaconda, Death Adder and Black Mamba.

The original Sidewinder, Seth Voelker, first appeared in Marvel Two-in-One #64 (Jun 1980), and was created by writers Mark Gruenwald and Ralph Macchio and artist George Pérez.

Alongside the third incarnation of the Serpent Squad, Sidewinder was able to return the crown to company president Hugh Jones, after a battle with the Thing, Stingray, Triton, and the Scarlet Witch.

[7] Sidewinder later rescued Black Racer, Copperhead, Fer-de-Lance, and Puff Adder from jail, and enlisted them in the Serpent Society.

[13] Sidewinder retired from villainy to allow Captain America to help him get money for his daughter, who was ill with cancer.

Captain America and Iron Man infiltrated the "think tank" to procure a special flash drive.

When Sidewinder and the villains present were defeated, Captain America and Iron Man found that Mockingbird secured the flash drive.

[17] Gregory Bryan had been turned into the new Sidewinder by the Brand Corporation under the orders of Hugh Jones and was a member of the Serpent Society.

After Gregory left, Cobra used the Brand Corporation's equipment (which had been long stolen by the Serpent Society) to create more Sidewinders.

The Society held a number of civilians hostage in a compound in the American Midwest claiming they were protecting themselves from the Skrulls.

[23] During the "Opening Salvo" part of the Secret Empire storyline, Sidewinder was with Serpent Solutions at the time when they are recruited by Baron Helmut Zemo to join his Army of Evil.

[24] Sidewinder possesses a cloak, created by scientists at the Roxxon subsidiary Brand Corporation's mutagenics laboratory and based on Nth Projector technology, which contains electronic circuitry that enables the wearer to open an aperture into another dimension.

Sidewinder's armor provides protection against small-arms fire and a rebreather unit allowing him to survive underwater for extended periods.

[27] The Seth Voelker incarnation of Sidewinder appears in Captain America: Brave New World (2025), portrayed by Giancarlo Esposito.