The siege of Trepča was a successful assault by Mehmet the Conqueror in the second Serbian campaign in 1455.

While those in the West gave up the crusade, Sultan Mehmet started his second Serbian expedition, despite the peace treaty.

[1] In addition, as soon as Mehmet returned to Edirne, Hungarians and Serbs took up arms and captured the environs of Niš and Kosovo.

[2][page needed] The Serbian leader, as in 1454, did not offer open resistance.

Georg took his wife and children and a few people from the palace and crossed the Danube to Hungary, where he had lands and castles in the south.