During Sultân Süleymân's 1543 campaign into Hungary, the Ottoman army first took Valpovo, in Slavonia, on June 23.

Süleymân then sent his army north of the Drava River to take Siklós, which belonged to the Perényi family [hu], who, during the civil war raging in Hungary, was on the side of King Ferdinand I of Habsburg.

Either on June 24 or 25, Siklós was given an opportunity to surrender but the garrison, led by castellan Mihály Vas, refused.

[1]  On June 26, Siklós was besieged, bombarded, and attacked but the garrison stood strong.

On July 6, after 3,000 cannonballs had hit the fortress, the garrison surrendered, and Süleymân entered the city the next day.