It was built just north of the Frontier hotel-casino, and they both shared the same ownership, although the Silver Slipper's gaming operations were later leased out.

It was demolished shortly thereafter to become a parking lot for the Frontier, with plans to eventually rebuild the Silver Slipper as a high-rise hotel and casino, although this did not pan out.

Agents of the Nevada Gaming Control Board raided the Silver Slipper for using "flat" dice.

[19] The Silver Slipper entered foreclosure in January 1965,[20] but plans by the IRS to sell it were halted after the Frontier owners filed suit, noting that they owned the land and structure.

[21] Shelam Inc., a group led by local gambler Sam Diamond,[22][23] soon took over the casino's lease,[24][25][26] reopening the property on October 20, 1965.

[30][31] Businessman Howard Hughes took over the Silver Slipper's gaming operations in 1968, leasing the rights from Shelam for $5.3 million.

[34] Litigation ensued starting in 1974,[42] when the owners filed a suit against Hughes, alleging he was behind on a year's worth of rent.

[44] In December 1987, Summa agreed to sell the Frontier and the Silver Slipper – the last of Hughes' Las Vegas gaming properties – to casino owner Margaret Elardi.

[45][46] Summa continued operating the Silver Slipper until its closure on November 28, 1988, at which point Elardi took over the property.

[49] Elardi redeveloped the land as a parking lot for the Frontier,[50][51] and planned to eventually construct a new Silver Slipper on the site, in the form of a high-rise hotel-casino.

These stories originated with a 1967 article by columnist Earl Wilson, who wrote:[62][63] [Hughes] found the lights of the Silver Slipper, across the Strip, interfered with his sleep.

[62][63] Hughes himself never wrote of the neon slipper in his extensive archive of memos,[62] and concrete was never found in the rotating mechanism.

[64] In 2009, the slipper was installed on a median along North Las Vegas Boulevard, in front of the Neon Museum.

[65] In 2018, the museum changed the slipper's sole and insole paint from red to blue, matching the original color scheme according to early photographs.

It was purchased by the Exchange Club casino in Beatty, Nevada, and was relocated there to mark its parking lot, before being toppled by strong wind in 2018.

[71][72] Other entertainers included singers Fifi D'Orsay, Nellie Lutcher and Rusty Draper, and comedians Billy Gilbert and Buster Keaton.

[80][81][82] It featured a variety of female impersonators, including Kerr,[53] who portrayed singers such as Barbra Streisand and Cher.