Featuring a title character who becomes super-powered due to genetic mutation, the series continued Kirby's run of creator-owned work.

The series was launched following the success of Kirby's previous creator-owned book for Pacific, Captain Victory and the Galactic Rangers.

In the six-issue series Silver Star teams with fellow "Homo Geneticus" Norma Richmond (gifted with the ability to resist enormous stress) and Big Masai (a size changing mutant), and battles with the villainous Darius Drumm, an early subject of Dr. Bradford Miller's genetic structuring with the ability to warp reality.

[2] Unlike the initial run of Marvel Comics' X-Men, also done by Kirby, in which the cast remains intact, the story kills off two potential members of the team before Silver Star could recruit them (one by an exploding baseball, the other by a circus act gone wrong), in issues #3 and #4.

In November Dynamite published a 6-issue tie-in Kirby Genesis: Silver Star miniseries, by writer Jai Nitz and artist Johnny D, featuring covers by Alex Ross, Jae Lee, and Mark Buckingham.

The White House sends a high-ranking man, Floyd Custer, to make a report - they both find Miller unconscious.

Miller is astral-travelling through several worlds to meet with the girl, Tracy, thanking her for the song but explaining that it will be dangerous for her to contact him again in the future: there is an imminent threat - a man who is hiding at that point.

Miller then reveals to Hammer that his superhumans can alter their aging: Silver Star looks no older than he was in Vietnam War (apparently ten years have passed since), and Drumm himself is a child in a man's body.

Three gangsters - Sugar Man; Macho, the Flash; and Roswell Baggs - want to shake Frye off but, when they try using thugs and semiautomatic weapons, Frye becomes a 30-foot giant and gets rid of Sugar Man, then going after Macho, while Silver Star has a drink at a local bar, sharing philosophy with the bartender.

Finally sick of waiting, Silver Star matches Big Masai's size, confronts him, and insists on the urgency of his quest.

The sectarians also try to keep Norma captive, but she is too strong and brazen for them – only Drumm's threat are useful, as her powers are not developed enough to match his.

Drumm explains his anti-social view and how his sect will get rid of perceived hedonists - albeit he had told Norma, and would tell Silver Star later, that he intended to wipe all the homo sapiens from the face of Earth.

Meanwhile, the USAF - alerted by Dr. Miller - attacks the Angel of Death, but they are unable to stop him from destroying suburbs and several areas.

The Angel of Death reaches Redlands City, population ten million and, when he starts to kill people in the crowd - he sees that all of them have Darius Drumm's face - this is later revealed to have been an illusion staged by Silver Star.