Born in Macerata, Spaccesi studied in a Salesians of Don Bosco School, and made his official theatrical debut with the stage company held by Angelo Perugini.

[2] He was best known for the musical comedy Forza venite gente, in which he played the role of Pietro di Bernardone, Francis of Assisi's father.

He voiced Yoda in the Italian versions of the Star Wars original trilogy and Santa Claus in The Nightmare Before Christmas.

Spaccesi often dubbed actors such as Gustav Knuth, Charles Durning, Frank Oz and Jack Warden in a select number of their films.

[5] Spaccesi died in Rome on June 2, 2015, at the age of 88 just a few days after the death of his partner Rosaura Marchi.