The wood is generally insect resistant and is used in the preparation of quality furniture, toys, matches, and as pulp (in paper making).

[3] Though there is some research[4] claiming that Simarouba is effective for treating certain diseases, there seems to be insufficient evidence[5] of curing diarrhea, malaria, edema, fever, and stomach upset.

However, to date, no systematic research using phytochemicals isolated from Simarouba glauca has been carried out to explore the molecular mechanisms leading to cancer cell death.

[citation needed] Simarouba extracts are known to be effective only on specific types of human cancer cell lines and tests conducted were in vitro.

Whether the same effect would be observed under in vivo conditions, depends on bioavailability and bioaccessibility;[citation needed] hence, Simarouba as an alternative cure for cancer remains unproven.