Simeon Ampatuan Datumanong (June 17, 1935 – February 28, 2017) was a Filipino Muslim politician who held different government positions including being a representative of the lone district of Maguindanao in the House of Representatives of the Philippines.

He was married to Hadja Sittie Mariam Sigrid de Guzman Datumanong and had four children.

Right after finishing high school, he took up Bachelor of Laws at the University of the Philippines.

Datumanong entered politics when he was elected as Vice-Governor (1963–1967) then as Governor (1967–1971) of Cotabato.

He served until 2001 when he was appointed by President Gloria Macapagal Arroyo as Secretary of Public Works and Highways.