After the termination of a vast amount of international routes in recent years it handles flights to several destinations in Central and South America as well as few services to Europe, Russia, China and Turkey.

Commencing in the late 1970s, Air France operated weekly Concorde service between Caracas and Paris via a stop at Santa Maria Airport located in the Atlantic Ocean.

As part of an expansion plan, new international gates are currently in construction, and a section of the parking area has been cleared to build an airport hotel.

In the 1950s under the regime of Marcos Pérez Jiménez, road transport between the airport and the capital was improved by the inauguration of the Caracas-La Guaira highway.

[11] Airlines have left for other reasons, including crime against flight crews, stolen baggage, and problems with the quality of jet fuel and maintenance of runways.

[citation needed] Following the increasing economic partnership between Venezuela and Turkey in October 2016, Turkish Airlines started offering direct flights from December 2016 connecting between Caracas to Istanbul (via Havana, Cuba) in an effort to "link and expand contacts" between the two countries.

[14] In support of President Nicolas Maduro's government, Russian Air Force aircraft, including Tupolev Tu-160 bombers, were deployed to the airport in early December 2018.

For fear of safety, some carriers have avoided overnight flight crews in Caracas, choosing to make a stop in a nearby country instead.

[14][59] The chronology of terminations is as follows:[60] 7 April 2014 (1st) 28 February 2024 (2nd) 31 July 2024 From 1960 to 1997, it was the main hub for Viasa, Venezuela's former flag carrier until it went bankrupt in January 1997.

However, due to financial crisis in Venezuela, several pilots quit and are leaving Conviasa in order to fly to other nations like Turkey which operates the same type of aircraft.