On 5 August 2006, Simone moved to Serie A newcomer Torino[7][8] after the club signed Mark Bresciano and Fábio Simplício from Parma.

Barone debuted for the Italy national football team on 18 February 2004, in a 2–2 friendly tie against Czech Republic in Palermo.

Stefano Bettarini and Sergio Volpi also received their first call-up[10] and made their debut under manager Giovanni Trapattoni during the match.

[15] In total, Barone made 16 appearances for Italy between 2004 and 2006,[16] scoring his only international goal on 9 February 2005, in a 2–0 friendly home win over Russia, in Cagliari, at the stadio Sant'Elia.

[18][19][20][21][22] In late June 2016, Barone was appointed assistant manager for Indian Super League club Delhi Dynamos, under his former international teammate Gianluca Zambrotta.