[1] Simone began her career in Campeonato Brasileiro's Ponte Preta, Santos FC and Saad EC.

In 2010, she returned to Brazil, playing for Novo Mundo FC, but two years later she signed for Energiya Voronezh in the Russian Championship.

[3] In June 2019 38-year-old Simone left FC Metz after five seasons and retired from playing football.

[4] In June 2000 Simone made her international debut in Brazil's 8–0 CONCACAF Women's Gold Cup win over Costa Rica at Hersheypark Stadium, Hershey, Pennsylvania.

She also participated in the 2008 Summer Olympics, again helping Brazil finish one spot short in second place.