Sims is a science fiction novel by American writer F. Paul Wilson that explores a near-future event where Humanzees (Human-Chimpanzee hybrids) are created as a de facto slave race.

The SimGen Corporation has created a transgenic species called SIMS, creatures that are part chimpanzee and part human, and are treated as slaves.

Suddenly a group of sims working as caddies at a golf course decide they want to unionize.

They hire lawyer Patrick Sullivan to represent them, and Sullivan begins to ponder whether or not sims are entitled to equal human rights.

During the course of the novel, Patrick meets activist Romy Cadman and a mysterious man called Zero, who are on a crusade to destroy SimGen and stop the creation of sims.