[3] Burke trained as a primary school teacher, graduating from Marino Institute of Education at the top of her class and winning the Vere Foster medal[4] and holds a Masters in Broadcast Production for TV and Radio from IADT.

[6] Burke was invited to attend the White House for an event titled 'Design for all' where the Obama administration highlighted the intersection of fashion and disability.

[10] She was one of 15 women selected to appear on the cover of the September 2019 issue of British Vogue, by guest editor Meghan, Duchess of Sussex.

[14] Burke appeared on the long-running BBC Radio 4 programme Desert Island Discs (hosted by Lauren Laverne) on Sunday 17 May 2020.

"[16] In October 2019, Burke released As Me with Sinéad, a podcast series from the Lemonada Media network[17] focused on empathy, identity, and perception through in-depth interviews.

[18] Guests of As Me have included Victoria Beckham, Jamie Lee Curtis, Jameela Jamil, Hozier, Akilah Hughes, Riz Ahmed, Mara Wilson, Radhika Jones, Tig Notaro, Dan Levy, and Florence Welch.