Often celebrities appeared performing previously unknown talents, such as actor French Stewart singing and dancing Hooray Pornography, Andy Dick tap-dancing, or Jerry Springer singing while the dancers fight behind him a la The Jerry Springer Show.
Musical highlights were Fred, an old-time barbershop quartet, singing "I Wanna Be Sedated"; Michael McKean as a distraught Edgar Allan Poe who breaks into a disco extravaganza with the Eight Deadly Sin Dancers', and comedian Carlos Alazraqui transforming the tradition of Irish River Dancing into a bizarre S&M spanking fantasy—which were the brainchild of writer Martin Olson.
In one performance, Popper jammed on the harmonica while Penn narrated a story and Teller illustrated it with card tricks.
Other performers included comedians Kevin Meaney, Don Novello, Otto and George, Bobcat Goldthwait, Eric Idle, and Martin Mull.
Some of their pieces, like "Cuffed to a Creep" where Penn finds himself handcuffed to a bizarre stranger (Teller) on a park bench, and "Balloon of Blood" in which Penn eloquently describes the strength and vulnerability of humanity, were borrowed from their stage show, while others, like Teller's "zippo lighter" piece, were written especially for the TV show.