Sinclair House was a 19th-century hotel which stood at 754 Broadway[1] and Eighth Street in Manhattan, New York City.

[4] Part of what became the Sinclair House was constructed around 1787, on land purchased by Frederick Charles Hans and Baron Bruno Poelintz from John Jay, Isaac Roosevelt, and Alexander Hamilton.

The restaurant in the hotel was well known, described by one New York paper in 1920 as "celebrated for its toothsome terrapin, its canvasback ducks, its turtle soup, its oyster and tripe stews, no less than for its more plebeian corned beef and cabbage.

"[14] Francis Marion Crawford's novel Katharine Lauderdale was partially written while he stayed there, and its events are laid out in the same neighborhood.

[15] The same month the establishment was the location of delegate selection of several conventions pertinent to the 5th Ward Union Association.