He found that having an extra receiver on the line forced defenses to choose their poison by either defending the pass or the run because they were not able to focus on both at once using the number of personnel that they had on the field.
He also then began utilizing sets of two tight ends as blockers mainly to protect his quarterbacks from Lawrence Taylor.
By using different formations and motion before the ball was snapped, he also found that he could confuse defenders on whether the play would be a pass or a run.
Speed offenses will use single back because the defense still has to respect the run out of these formations since you can line up many tight ends and still have a down field passing game.
Linebackers will often have to cover receivers in passing routes while defensive safeties are used more to come up and stop the run on the line of scrimmage.