Moss's older brother, Santana, is a former wide receiver who played in the NFL for 14 seasons as a member of the New York Jets and Washington Redskins.

[1] Moss played college football for the University of Miami Hurricanes, where he was a standout wide receiver.

Moss was selected by the New York Giants with the 44th overall pick in the second round of the 2006 NFL draft out of the University of Miami.

[4] The Giants expected to groom Moss to be their slot receiver in 2006 but his progress was marred by a recurring quadriceps injury, which caused him to miss training camp and limited him to five receptions during his rookie season in six games.

During the preseason, Moss competed for the return specialist job, but suffered from a sports hernia and on August 31, 2010, was placed on season-ending injured reserve.