This cultivation technique was developed in Sinaloa, Mexico, in the 1970s, by the drug trafficker Rafael Caro Quintero[1][2] and consists of separating male plants as soon as they are known to be male, in order to avoid pollination of female pistils.
[3] The seeds are not useful for recreational purposes and require the plant to make a great expenditure of energy that could be invested in increasing the tetrahydrocannabinol (THC) of the inflorescences (buds).
Regular use of high potency cannabis (HPC) has been linked in several studies to an increased likelihood of psychotic disorders.
[7][8][9] A 2015 study looked at multiple users of skunk, sinse or other HPC cannabis strains in South London showed a corresponding relationship with adults presenting with episodes of psychosis similar to schizophrenia.
[9] New research, carried out since the liberalisation of the harsh laws prohibiting cannabis, suggest that rather than being a cause of psychotic conditions the non-psychoactive cannabinoid compound, cannabidiol (CBD), may in fact have an anti-psychotic effect.