Until 1881 the college was located in the birthplace of Philippe Piers de Raveschoot (mayor of Ghent 1819-25 and 1865-81) in the Koningstraat.
In 1881 the school moved to its present location on the Zilverenberg, close to the confluence of the rivers Leie and Scheldt.
The house was later inhabited by senator Jan Vergauwen, one of the members of the Belgian National Congress that drafted the 1831 Constitution.
The number of pupils increased and by the end of the 19th century the school gained its look that it maintained until the 1950s-1960s, under the impulse of then superior Rev.
The school also bought the sporting facilities Westveld on the border of the municipalities of Destelbergen and Sint-Amandsberg (the Nachtegaalstadion).
The school has its own groups within the youth organisations Katholieke Studenten Actie (KSA) and scouts (VVKS).
In the same period, the primary school of the Sint-Lievenscollege moved to buildings in the Keizer Karelstraat, until today its location.