Sinŭiju (Korean: 신의주시; MR: Sinŭiju-si; IPA: [ɕinɰidzu ɕi]), is a city in North Korea which faces Dandong, Liaoning, China, across the international border of the Yalu River.

Part of the city is included in the Sinŭiju Special Administrative Region, which was established in 2002 to experiment with introducing a market economy.

In recent years, the city, despite lagging behind the development in the capital Pyongyang, has seen a small construction boom[contradictory] and increasing tourism from China.

The city is currently divided into 49 tong (neighbourhoods) and 9 ri (villages): Developed as a major settlement during the colonial rule at the terminus of a railway bridge across the Amrok River, Sinuiju is located 11 km (7 miles) south by southwest of Ŭiju, the old city from whose name Sinŭiju (meaning “New Ŭiju”) derives.

A substantial portion of North Korea's international trade, both legal and illegal, passes through Sinuiju and Dandong, across the Yalu River.

Foreign tourists on excursion boats from Dandong are sometimes permitted to approach within a few meters of the city's coastline, as long as they do not land.

It formerly had another line running from the Sinuiju Chongnyon Station to Ragwon Machine Complex that closed between 2005 and 2009 with the reconstruction of the highway with a shifted alignment.