Its location near the Mithi River means that the railway between Sion and Kurla, directly to the north,[2] has flooded frequently during the Indian monsoon.

However, in 2019, the Central Railway conducted work to raise the trackbed by four to six inches to prevent future flooding.

Sion was one of the stations for the First Passenger Train of India (the second stop), that ran on 16 April 1853, where its engines were 'watered' and its wheels greased.

[5] The original Sion station was not situated at its present site, but was somewhere close to Kurla.

Therefore, in 1872, 107 local inhabitants from Sion and nearby villages sent a petition to the Railway Company (GIPR) to request a station be built.