The Santa Anita Mathis Mile Stakes is a Grade II American thoroughbred horse race for three-year-olds over a distance of one mile on the turf held annually in late December Santa Anita Park in Arcadia, California, USA.
The inaugural running of the event was on 26 December 2000 as the Sir Beaufort Stakes, opening day of 2000–01 Santa Anita Park's Winter meeting.
The event attracted eight entrants and was won by Edmund A. Gann's Fateful Dream, who was trained by US Hall of Fame trainer Bobby Frankel and ridden by US Hall of Fame jockey Kent Desormeaux by one length in a time of 1:35.01 on a turf course that was rated as firm.
[1] The event was named after the 1993 Santa Anita Handicap winner Sir Beaufort.
In 2003 the event was moved off the turf and run on a dirt track.