He was in leading physician's practice in London along with John Freind, Richard Mead, Hans Sloane, and others.

He retired from practice some years before his death, and lived at his house on Dartford Heath, Kent.

In his old age he was possessed by the idea that he would die of want, a fear which his attendants overcame by putting guineas regularly into the pocket where he used to deposit his fees.

He married, in 1713, Elizabeth, daughter of Sir Richard Levett, knt., who had been lord mayor in 1700, and had issue by her.

His son Edward, who succeeded to the title, was father of Sir Samuel Hulse.