Sir Francis Pile, 2nd Baronet (c. 1617 – 1649) was an English politician who sat in the House of Commons between 1645 and 1649.
Pile was the son of Sir Francis Pile, 1st Baronet of Compton-Beauchamp and his wife Elizabeth Popham, daughter of Sir Francis Popham.
Pile married firstly Mary Dunch, daughter of Samuel Dunch of Pusey, Berkshire, and secondly on 18th July 1639 Jane daughter of Rt Rev.
John Still, Bishop of Bath and Wells.
His son died young and with daughters remaining the baronetcy passed to his brother Seymour.