Sir George Seymour was built in Sunderland, Tyne and Wear in 1844 by Somes Brothers.

On 4 November 1844 Sir George Seymour, John Young Clarke, master, set sail from England, bound for Van Diemen's Land, Australia; she arrived at Hobart on 27 February 1845.

Sir George Seymour sailed from Plymouth on 9 January 1849, bound for Geelong, Victoria.

Sir George Seymour left Plymouth Sound, England around 11 am on Sunday, 8 September 1850, with about 227 passengers.

However, she sailed closer to the coast of the South Island than her sister ships and dropped anchor in Port Victoria (off Lyttelton) at 10 am on Tuesday, 17 December 1850, a day later than Charlotte Jane.

[7][additional citation(s) needed] The ship is remembered in the name of a road, George Seymour Quay, in the port town of Lyttelton.