Sir George Wakeman (died 1688) was an English doctor, who was royal physician to Catherine of Braganza, Consort of Charles II of England.
In 1678, in the allegations of the fabricated Popish Plot, he was falsely accused of treason by Titus Oates, who had gained the backing of Thomas Osborne, 1st Earl of Danby, the effective head of the English government.
Oates accused Wakeman of conspiring to kill the King with the help of the Jesuits, and to put his brother James, Duke of York on the throne in his place.
Also, once the initial hysteria caused by the Plot died down, it became clear to most rational people that Wakeman's record of unblemished loyalty to the Crown was utterly inconsistent with the charges of treason made against him.
John Evelyn, a personal friend of his, was no doubt one of many who accepted that there was a Plot of some sort but refused to believe that Wakeman, "so worthy a gentleman", had any part in it.
[1] In their perjured narrative of the Popish Plot, Titus Oates and Israel Tonge declared that Wakeman had been offered £10,000 to poison Charles II's posset, and that he could easily effect this through the agency of the Queen.
Then, they said, he attended the "Jesuit Consult" on 30 August 1678, received a large sum of money on account, and, the further reward of a post as physician-general in the army having been promised him, he definitely engaged to poison the king.