Sir James Colville of Easter Wemyss (died 1540) was a Scottish administrator, lord of session and diplomat.
He was nominated a lord of the articles on 13 May 1532 and 7 June 1535, and at the latter date was chosen a commissioner for the taxation of £6,000 voted by the three estates to James V of Scotland on his approaching marriage.
[3] On the institution of the College of Justice in 1532, Colville was appointed one of the judges on the temporal side of the bench, and was knighted.
In November, the English border official Thomas Wharton heard that the secretary Adam Otterburn of Auldhame was imprisoned at Dumbarton Castle for speaking with the banished Douglas family and James Colville was in prison for "his accomptes".
He disobeyed this order, and, back in England, associated with Archibald Douglas, 6th Earl of Angus, and his brother in treason attempts against the Scottish king.