Sir Thomas Littleton, 2nd Baronet (c. 1621 – 14 April 1681) was an English politician from the extended Littleton/Lyttelton family who sat in the House of Commons variously between 1640 and 1681.
Littleton was the son of Sir Adam Littleton, 1st Baronet of Stoke St. Milborough, Shropshire and his wife Audrey Poyntz daughter of Thomas Poyntz.
In 1652 he sold the Stoke St. Milborough estate to Henry Bernard.
[3] After the Restoration, Littleton sat for Wenlock again in the Cavalier Parliament from 1661 to 1679.
Their son and heir, Sir Thomas Littleton, 3rd Baronet, became Speaker of the House of Commons.