Sissonville is a census-designated place (CDP) in Kanawha County, West Virginia, United States, along the Pocatalico River.

The flooding in 2000 claimed three lives when a boat belonging to the Charleston Fire Department capsized during a rescue attempt in the 2900 Block of Sissonville Drive.

The history of flooding in the area was the impetus for the closing of Bonham Elementary School located along Kanawha Two Mile.

[8] In October 2001, the Katie Sierra free speech case made national news when a Sissonville High School student was reportedly suspended for her activism in opposition to the bombing of Afghanistan.

The largest employer in the Sissonville area is the Nippon Tokushu Tōgyō (Niterra in English) North America Manufacturing facility located near the Sissonville-Pocatalico Exit of Interstate 77.

The facility employs over 400 full-time workers manufacturing spark plugs and oxygen sensors.

Columbia Gas operates the Lanham Compressor Station located at the intersection of Kelly's Creek Road and Martin's Branch.

{http://columbia-gas-transmission-wv-59.hub.biz/} Cabot Oil & Gas operates the other compressor station located on Derrick's Creek Road near Edgewood Country Club.

The facility houses animal health labs and one of the Department's Regional Response Teams for dealing with agricultural emergencies.

The school is designed to provide practical, hands-on training to first responders in all phases of emergency response.