[1] It elects one deputy to the lower house of Congress for each three-year legislative period by means of the first-past-the-post system.

Votes cast in the district also count towards the calculation of proportional representation ("plurinominal") deputies elected from the third region.

[1] The 6th district was created as part of the National Electoral Institute's 2022 redistricting process to reflect shifting population dynamics across the country.

[5][a] The district's head town (cabecera distrital), where results from individual polling stations are gathered together and tallied, is the state capital, the city of Mérida.

With Indigenous and Afrodescendent inhabitants accounting for over 47% of that number, Yucatán's sixth – like all the state's electoral districts, both local and federal – is classified by the National Electoral Institute (INE) as an indigenous district.