The fiction follows the lives of a group of teenagers (most notably Eva, Cris, Nora, Viri and Amira),[1] who study at the IES Isabel la Católica [es] high school near El Retiro, in Madrid,[2] dealing with issues such as shame, loneliness, self-acceptance, bullying, bisexuality, feminism, empowerment, sorority and toxic relationships.

[8] The first season follows Eva Vázquez Villanueva, a teenager who spends the summer with her boyfriend, Jorge, and his best friends, Lucas, Hugo, and Dilan.

The topics covered in Eva's season are mistrust, feminism, cyberbullying, rejection of friends, personal dependency, toxic relationships, and friendship.

In a break from tradition with the original Skam, Season 3 has two central protagonists, Nora Grace and Elvira "Viri" Gómez García.

This season centers on her struggles to balance her religion with her identity, as well as her burgeoning romantic relationship with Dani, Cris' older brother, and a non-Muslim.

Due to the coronavirus outbreak, Skam España drops the real-time format; as a result, the events of Season 4 are taking place in April 2020, despite the show airing in September 2020.