Skilesville is an unincorporated community in Muhlenberg County, Kentucky, United States.

Skilesville is located on the Green River and Kentucky Route 70 on the eastern border of Muhlenberg County, 0.6 miles (0.97 km) west of Rochester.

[2] A post office called Skilesville was established in 1878, and remained in operation until 1907.

[3] The community was named for James Skiles, a riverboat operator.

This Muhlenberg County, Kentucky state location article is a stub.